Michael D. Hogarty, M.D., is a Professor of Pediatrics at the Children's Hospital of Philadelphia, specializing in the treatment and research of childhood cancers, specifically neuroblastoma. His research aims to identify key oncogenic pathways to develop new therapeutic strategies for pediatric solid tumors. His laboratory focuses on two main projects: one examining the role of polyamines in neuroblastoma pathogenesis, and the other investigating the Bcl2 family proteins' influence on cancer cell stress responses and therapy resistance. Dr. Hogarty's clinical expertise encompasses managing neuroblastoma and related histiocytic diseases in children. He holds prominent roles in numerous international research organizations, including the Children's Oncology Group and the International Neuroblastoma Research Group, contributing to advancing the understanding and treatment of neuroblastoma through clinical and translational research. His work incorporates innovative approaches such as utilizing preclinical models and identifying molecular biomarkers to aid in therapy selection.