Dr. Hao Wu's research focuses on mechanistic immunology, particularly the structural regulation of innate immune pathways, emphasizing the inflammasome pathway. His work employs advanced imaging techniques such as cryo-electron microscopy to elucidate molecular structures and functions within these immune complexes, aiming to reveal crucial insights into the dynamics of immune responses. Dr. Wu has significantly contributed to the understanding of the NLRP3 inflammasome and its activation mechanisms. His recent publications in high-impact journals, such as Nature and Cell, demonstrate his commitment to advancing knowledge in immunology, particularly concerning the signaling pathways that govern inflammatory responses. As a recognized expert in the field, Dr. Wu has received several prestigious awards, such as the Gregori Aminoff Prize and the Bert & Natalie Vallee Award in Biomedical Science.
Harvard Medical School / Boston Children's Hospital • Boston, MA
Leading research on mechanistic immunology and director of the Wu Lab.