Dr. Robert S. Kass is a leading figure in the field of Molecular Pharmacology and Therapeutics at Columbia University's Vagelos College of Physicians and Surgeons. His academic career began with a Bachelor of Science in Physics from the University of Illinois, Urbana, followed by a PhD in Physics from the University of Michigan, Ann Arbor. Over four decades, Dr. Kass has made significant contributions to the understanding of cardiac electrical activity through a multidisciplinary approach that intersects basic biophysics and clinical science. His research centers on the structure-function relationships of ion channels, particularly in relation to cardiac arrhythmias caused by inherited mutations. Dr. Kass's laboratory investigates the molecular physiology of these channels, focusing on potassium ion channel mutations and their connection to diseases such as heritable pulmonary arterial hypertension. His work not only aims to elucidate the fundamental mechanisms behind these disorders but also seeks to develop targeted therapeutic strategies informed by genetic factors. Additionally, Dr. Kass emphasizes collaborations with clinical colleagues to integrate laboratory findings into practical clinical applications, enhancing patient management through a mutation-specific therapeutic approach.