Franziska Bleichert's research focuses on understanding the operating principles of macromolecular machines involved in chromosome replication and maintenance, as well as genome stability. Utilizing a combination of structural biology, biochemical, biophysical, and cellular approaches, Bleichert explores these complex processes. She obtained her PhD from Yale University in 2010, where she worked on ribosome biogenesis. Following this, she performed postdoctoral work at the University of California, Berkeley as a Miller Fellow before continuing her research at Johns Hopkins Medical School. There, she determined the structure of the eukaryotic initiator complex, a crucial component in the assembly pathway of DNA replication machinery. In 2017, she became the independent research group leader at the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, and subsequently joined Yale’s Department of Molecular Biophysics and Biochemistry as an Assistant Professor in January 2020.