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The Bowman Lab at the University of Pennsylvania focuses on understanding the evolution of leukemia through innovative genomic approaches and advanced model systems. By employing sophisticated mouse models alongside synthetic biology and computational techniques, the lab aims to delineate the mechanisms that drive clonal evolution in cancer. Through single cell biology methods, the lab seeks to uncover the intricate rules governing the development and progression of leukemic cells, ultimately working towards strategies to impede cancer evolution. The interdisciplinary approach integrates various scientific fields to ensure a comprehensive understanding of leukemia, facilitating potential breakthroughs in treatment and patient care.
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