Zhixun Dou is an Assistant Professor in the PhD Program in Biological Biomedical Sciences at Massachusetts General Hospital. His research focuses on understanding the mechanisms of nuclear degeneration in the context of aging and cancer. His lab investigates cellular senescence, inflammation, autophagy, and epigenetics as they relate to aging and cancer. Dou's research highlights the role of senescent cells in age-associated diseases by studying their contribution to inflammation and the activation of immune responses. One key area of interest is nuclear autophagy, where he aims to reveal how nuclear materials degrade through autophagy and its implications in aging. Dou also investigates the molecular and cellular mechanisms that contribute to chronic inflammation during aging, seeking novel therapeutic approaches to mitigate age-related diseases.
Massachusetts General Hospital • Boston, MA
Conducts research in the areas of aging and cancer, focusing on nuclear degeneration and cellular mechanisms.