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The Tsourkas Lab at the University of Pennsylvania focuses on creating novel targeted imaging and therapeutic agents for the detection and treatment of a diverse range of diseases, including cancer, cardiovascular disease, autoimmune disease, and infectious diseases. The lab emphasizes the development of targeted nanoparticle formulations and antibody protein-based agents. Specific research interests encompass developing new nanoformulations capable of carrying high payloads of drugs, radiosensitizing agents, photosensitizers, and contrast agents. Additionally, the lab works on bioconjugation techniques to enable highly efficient, site-specific labeling of proteins, antibodies, drugs, enzymes, and oligonucleotides. They investigate new targeting strategies to maximize specificity, accumulation at target sites, and tissue penetration. Their approach is designed to enable personalized medicine, improve diagnoses, and inform treatment planning while monitoring therapeutic efficacy. A significant focus is placed on overcoming practical, financial, and regulatory barriers associated with designing new agents, emphasizing scalability, modularity, cost, biodegradability, and safety.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.