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Adonis Skandalis is an Associate Professor in the Department of Biological Sciences at Brock University. His research primarily focuses on the mutagenic processes in genetic information that contribute to aging and disease. He conducts protein structure-function studies of enzymes involved in nucleic acid replication, processing, and repair. Two major areas of his research include the investigation of spontaneous fidelity in mRNA splicing across different ages and disease states, along with the examination of cellular defense pathways against aberrant transcripts. His lab utilizes DNA microarray technology to survey aberrant splicing and is involved in directed evolution studies to elucidate the structure-function relationships of enzymes related to the metabolism of DNA and RNA, including their roles in replication, repair, and splicing.
This entry applies to the general Graduate Studies standard for departments such as English Language and Literature, History, Philosophy, and Sociology.