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Ahmad Al-Mrabeh is an MRC Career Development Fellow at the University of Edinburgh. He obtained his PhD in Biology from the James Hutton Institute in Dundee in 2011. Following his doctoral studies, he held various research positions from 2011 to 2021, ultimately becoming a senior scientist at Newcastle University in 2019, where he focused on the mechanisms of remission in type 2 diabetes (T2D). In August 2021, he transitioned to the University of Edinburgh as a British Heart Foundation Transition Research Fellow, establishing his own research group. His work concentrates on investigating the mechanisms behind reversible pancreatic lipotoxicity in T2D, driven by a successful MRC Career Development Award in 2022. His research delves into the identification of toxic lipids causing pancreatic dysfunction, with the objective of developing novel diabetes therapies. Al-Mrabeh's program synthesizes clinical, preclinical (mouse), and ex-vivo studies to uncover the relationships between obesity, lipid metabolism, and T2D remission, emphasizing the role of de novo lipogenesis and its impact on lipoprotein export, pancreatic lipid deposition, and overall pancreatic health.
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