Dr. Åke Borg

Biography

Åke Borg is a Professor at Lund University specializing in breast cancer genetics. His expertise lies in understanding the complexities of breast cancer, a major malignant disease affecting women with a continuously rising incidence. Borg focuses on the genetic predisposition, tumor biology, and clinical course of breast cancer, emphasizing the need for biomarkers that can enhance diagnosis, prognostication, and treatment prediction. This approach is aimed at using precise drugs to minimize overtreatment. He works with new sequencing technologies that allow for comprehensive genome and transcriptome characterization, aiming to classify breast tumors into subtypes based on gene expression patterns, DNA methylation, nucleotide substitutions, and genomic rearrangements. Borg's research highlights the role of pathogenic germline sequence variants in major susceptibility genes such as BRCA1 and BRCA2, which confer a high relative risk and explain a significant portion of familial breast cancer cases. He advocates for the modern medicine approach that effectively translates new molecular research findings into clinical settings, fostering collaborations among scientists and clinicians. His work contributes to the UN Sustainable Development Goals pertaining to health and well-being, focusing on improving cancer treatments and outcomes.

Research Interests