Dr. Akira Imamoto

Biography

Akira Imamoto, DDS, PhD, is an Associate Professor in the Department of Cancer Research at the University of Chicago. His research primarily focuses on the mechanisms by which combination mutations affect broader cellular networks during development. He particularly investigates DiGeorge/Velocardiofacial/del22q11 syndrome, which arises in approximately 1 in 4000 live births and manifests through various cardiovascular defects, thymus and parathyroid gland aplasia/hypoplasia, craniofacial anomalies, urogenital defects, and psychiatric disorders. His work elucidates the roles of key genes such as TBX1 and CRKL within the context of this contiguous gene syndrome. By utilizing diverse techniques in his studies, Imamoto aims to establish functional links to signaling pathways involved in these syndromes. He has an extensive publication record that highlights his contributions to understanding signaling adaptors' roles in developmental processes.

Research Interests

Experience