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Akiva S. Cohen, PhD, is a Research Professor in the Anesthesiology Critical Care Department at the University of Pennsylvania. He specializes in understanding the fundamental cellular and molecular mechanisms that underlie cognitive impairments associated with traumatic brain injury (TBI). His research primarily focuses on alterations in neuronal excitability within the limbic system, which plays a critical role in higher cognitive functions such as learning and memory. Dr. Cohen employs a variety of research techniques including intracellular and extracellular recordings, whole-cell patch-clamp recording, and immunocytochemistry to investigate brain injuries and their impacts on cognitive function. Significant studies assess the hippocampal function in injured subjects, the influence of synaptic changes, and the quantification of cell death using unbiased stereology. His work aims to elucidate potential mechanisms driving cognitive deficits in brain-injured patients, paving the way for developing effective therapies to ameliorate these conditions.
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