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Alain Nepveu is a Professor in the Department of Biochemistry at McGill University. His research focuses on the biological roles and molecular functions of the CUX1 homeodomain protein in mammalian cells, particularly regarding DNA damage responses and cancer cell resistance to therapies. His laboratory employs a variety of molecular biology and functional genomic approaches combined with tissue culture and mouse models to explore how alterations in DNA repair mechanisms contribute to cancer progression. His work also involves investigating the CUX1 protein and its influence on the sensitivity of cancer cells to treatments such as radiotherapy and chemotherapy, aiming to leverage this knowledge to enhance therapeutic outcomes for patients. His extensive publication record includes studies on transcription factors, genomic instability, and the implication of CUX1 in breast cancer survival.
McGill University • Montreal, Quebec
Conducts research and teaches in the Department of Biochemistry.
Department: Department of Medicine. Program: Experimental Medicine.