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Alan Attie is the Jack Gorski Professor of Biochemistry at the University of Wisconsin-Madison. His research focuses on understanding the genetic and biochemical processes underlying metabolic diseases, with particular emphasis on obesity, diabetes, and lipid metabolism. His laboratory employs mouse genetics to investigate novel causal genes that lead to metabolic disorders. A significant aspect of Attie's work involves studying pancreatic β-cells and their role in insulin secretion in response to blood glucose levels. He is involved in projects that utilize global gene expression profiling to construct gene causal networks related to diabetes phenotypes. Attie's contributions to the field include exploring how genetic factors influence individual responses to diets, which can vary significantly among different mouse strains. He aims to identify genetic drivers that influence dietary responsiveness and metabolic outcomes, contributing to a broader understanding of diabetes and its related complications.
Department: Department of Computer Sciences