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Dr. Alan Brown is an Associate Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School. His research focuses on understanding transport mechanisms in cells, specifically the transport of molecules through cilia, which are finger-like organelles that project from the surface of eukaryotic cells. His work addresses the motility of cilia and their role in developmental signaling and sensory perception. Brown is particularly interested in ciliopathies, genetic disorders that affect cilia and can lead to conditions such as infertility, respiratory diseases, and polycystic kidney disease. His research employs a combination of structural, biophysical, and biochemical techniques, with an emphasis on high-resolution electron microscopy (cryo-EM). He has experience using similar methods to study ribosomal translation and is involved in developing new techniques to accelerate and improve cryo-EM structure determination, particularly in enhancing the interpretation of cryo-EM density maps to create accurate all-atom models.
Harvard Medical School • Boston, MA
Teaches and conducts research in the field of biological chemistry and molecular pharmacology.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.