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Alan Underhill is a Professor in the Department of Oncology at the University of Alberta's Faculty of Medicine & Dentistry. His research focuses on the role of histone modifications in regulating genome structure and function, particularly in relation to disease. His lab investigates how epigenetic controls influence crucial developmental processes in cancer and other disorders. Underhill's work utilizes various approaches, including genetic, molecular, and biochemical techniques, to explore the modulation of chromatin structure through methylation of specific histones. He is particularly interested in understanding the defects in regulatory pathways that contribute to breast cancer progression, pediatric gliomas, and neurodevelopmental disorders. Underhill's research has received funding support from several notable organizations, including the Cancer Research Society and the Canadian Institutes of Health Research. He is also involved in teaching courses such as ONCOL 520, ONCOL 425/525, and ONCOL 620.
Department: Mechanical Engineering and Engineering Management