Dr. Albert Edge

Biography

Albert Edge is a prominent researcher at the Harvard Stem Cell Institute focusing on sensory biology and regeneration. His work aims to understand the complex molecular signaling involved in cell fate determination and the mechanisms underlying hair cell regeneration in the cochlea. Edge has investigated the unique ability of lower vertebrates to regenerate lost sensory cells and seeks to uncover how similar processes can be induced in mammals. His research highlights the role of supporting cells and their capacity to convert into hair cells through the activation of specific signaling pathways, such as Wnt signaling, and the modulation of transcription factors. By employing advanced techniques, including CRISPR and siRNA screening, he explores epigenetic changes that inhibit stem cell differentiation and strives to identify essential genes for hair cell fate acquisition. His work holds the potential to develop new therapies for treating hearing loss through the regeneration of sensory cells and the reconstruction of neural circuits in the auditory system.

Research Interests

Experience