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Alexander Harms studied Molecular Microbiology at the University of Basel, where he defended his PhD in 2015 under the supervision of Prof. Christoph Dehio, focusing on the evolution of bacterial toxins and virulence factors. He then worked for several years as a postdoctoral researcher with Prof. Kenn Gerdes at the University of Copenhagen, researching toxin-antitoxin systems in bacterial persistence. In 2018, he returned to Switzerland to establish his own research team on bacteriophages, hosted by Prof. Urs Jenal at the University of Basel. In 2023, he was appointed Assistant Professor, tenure track, at the Department of Health Sciences and Technology (D-HEST) at ETH Zürich. The Laboratory of Molecular Phage Biology investigates bacteriophages outside classical models and standard laboratory conditions. Utilizing innovative culture systems and advanced microbial genetics with newly isolated phages, the research aims to uncover and understand new biology from the viral dark matter that dominates the planet. The knowledge garnered is directly applicable to improving applications of bacteriophages against bacterial pathogens in food safety and clinical phage therapy.
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