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Prof. Klibanov obtained his Master of Science in Chemistry and a PhD in Chemical Enzymology from Moscow University in Russia. After years of postdoctoral research at the University of California at San Diego, he joined MIT as an Assistant Professor of Applied Biochemistry in 1979. His research emphasizes the mechanistic understanding of enzymatic catalysis in nonaqueous media. His work has led to the discovery of rules that allow enzymes to act vigorously as catalysts in organic solvents that contain water, resulting in enzymes acquiring remarkable new properties, such as enhanced thermostability and increased specificity. His recent studies have introduced a novel 'non-release' strategy that renders common materials permanently microbicidal, effective against a variety of pathogenic bacteria and fungi. Prof. Klibanov's ongoing research continues to explore the creation of material coatings with anti-viral and anti-sporal activities, as well as improving the delivery efficiency of plasmid DNA using modified polyethylenimine (PEI).
Massachusetts Institute of Technology • Cambridge, MA
Conducts research and teaches in the field of Biological Engineering, specializing in enzymatic catalysis in nonaqueous media.