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Dr. Alexander R. Mendenhall is an Associate Professor in the Department of Laboratory Medicine & Pathology at the University of Washington. His research focuses on alleviating age-related disease suffering by studying individual cells in live animals throughout the course of aging. The Mendenhall lab investigates how long-lived, healthy individuals manage to maintain functionality over extended periods and examines genetically identical humans, such as monozygotic twins, in order to understand variations in aging and disease susceptibility. Utilizing the model organism Caenorhabditis elegans, Dr. Mendenhall aims to discern whether physiological variation is intrinsic, chance-based, programmed, or heritable. The lab employs a spectral confocal microscope to investigate the causes and consequences of variation in gene expression within genetically identical populations. By generating a cell-resolution atlas of age-related changes in gene expression, the Mendenhall lab tests hypotheses that explore the mechanisms leading to cellular and organismal failures associated with natural aging processes and various disease models, including cancer and Alzheimer’s disease.
University of Washington • Seattle, WA
Teaching and conducting research in the Department of Laboratory Medicine & Pathology.
Standard Graduate School requirements for University of Washington apply to most departments listed unless specified otherwise by the program.