Professor Dr. Alexander Sobolevsky

Biography

Alexander Sobolevsky earned his PhD in Biophysics in 1999 from the Moscow Institute of Physics and Technology. He studied the mechanisms of gating in ion channel block at NMDA receptor channels using kinetic modeling and patch-clamp recordings from freshly isolated rat hippocampal neurons under the guidance of Professor Boris Khodorov. He completed a postdoctoral position in the lab of Dr. Lonnie Wollmuth at Stony Brook University, where he explored the functional architecture of ionotropic glutamate receptors (iGluRs) using the substituted cysteine accessibility method (SCAM). He further extended his postdoctoral training with Dr. Eric Gouaux at Columbia University and Oregon Health Science University, solving the structure of iGluR. In 2010, he joined the faculty at Columbia University as an Assistant Professor in the Department of Biochemistry and Molecular Biophysics, where he focuses on the structure and function of ion channels, particularly iGluRs and transient receptor potential (TRP) channels. He was promoted to Associate Professor in 2017 and to Professor in 2024.

Research Interests

Experience

Awards