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Alice Sijts' research focuses on cellular processes underlying immune defense against intracellular pathogens and tumor growth. She is an expert in proteasome biology and MHC class antigen processing, studying how inflammation-induced changes in the processing pathway support the development of protective immunity. Dr. Sijts translates this knowledge to develop novel immunotherapies and the generation of vaccines for 'hard-to-treat' emerging pathogens. She obtained her PhD from Leiden University in the Netherlands and has held research positions in Berlin, Germany, and Rochester, NY, USA, before joining the Faculty of Veterinary Medicine. Dr. Sijts receives funding from the Netherlands Organisation for Scientific Research (NWO) for her fundamental research in antigen processing and participates in European networks focused on developing novel antibody-based tumor therapies, as well as T-cell based immune assays for predicting immune protection in human cell-based 3D infection models. Additionally, she coordinates the Horizon2020-financed Innovative Training Network 'VacPath', which is aimed at developing novel vaccines to protect against intracellular bacteria and viruses.
Department of Psychology