Dr. Alison Gurney

Biography

Alison Gurney is a researcher specializing in pharmacology, particularly focusing on ion channels that regulate pulmonary vascular tone. Her work investigates the physiological roles and pharmacology of specific ion channels in pulmonary artery smooth muscle cells. Gurney has contributed significantly to the understanding of mechanisms that regulate the diameter of small arteries in the lungs, which is crucial for determining blood flow resistance and pressure. She employs an interdisciplinary approach, using techniques such as small-vessel wire myography, electrophysiology, and molecular biology to study and manipulate ion channel expression and function. Past contributions include the discovery of KATP channels, TASK-1, and the identification of crucial signaling pathways involved in pulmonary arterial tone regulation. Gurney's research also assesses pharmacological interventions aiming to lower pulmonary arterial pressure, with implications for the treatment of pulmonary hypertension.

Research Interests