Dr. Amanda Kiliaan

Biography

Amanda Kiliaan is a Professor at Radboud University in the Faculty of Medical Sciences (Radboudumc), where she chairs the Anatomy department. Her research focuses on the intersection of obesity, high blood pressure, and vascular risk factors associated with brain disorders, including stroke and Alzheimer's disease. Kiliaan investigates the impact of nutrition on brain structure and function, particularly in relation to disorders affecting both mice and human subjects. Her central research theme examines the effects of various diets on neuronal systems across a spectrum from neural development to neurodegeneration and aging, with an emphasis on cerebral circulation and metabolism's relationship to cognitive disorders related to mood and memory. Kiliaan's research methodologies include the use of transgenic mouse models to explore neurovascular risk factors and the impact of dietary components on these disorders. She integrates neuroimaging techniques, such as Diffusion Tensor Imaging and resting state fMRI, to study cerebral hemodynamics and structural-functional connectivity in the context of learning and memory. Kiliaan collaborates with clinical partners in Neurology, Geriatrics, and Psychiatry, as well as industrial partners for translational research programs. Her work is part of a long-standing multidisciplinary EU consortium focusing on molecular, epidemiological, and clinical sciences, highlighting her commitment to understanding lifelong brain plasticity.

Research Interests

Experience