Dr. Amritpal Mudher

Professor

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Biography

Amritpal Mudher is a Professor of Neurosciences at the University of Southampton, where he serves as the Associate Dean for International Relations. His primary research interests involve investigating the mechanisms underpinning tau-mediated dysfunction and degeneration in tauopathies, particularly in Alzheimer's disease and fronto-temporal dementia. His work has led to the identification of disease-modifying tau-centered therapeutic targets and explores the pathological significance of tau aggregates and their soluble forms, as well as the effects of tau-mediated axonal degeneration. He utilizes various models, including Drosophila and human tissue, to investigate the interactions between type-2 diabetes and Alzheimer's disease, particularly the insulin resistance's impact on tau phosphorylation and aggregation. Additionally, he employs biophysical methodologies, such as AFM and Raman spectroscopy, to study tau aggregation in vitro and in models of tauopathies. He has served in multiple prestigious roles and has a comprehensive background as an Alzheimer Society Research Fellow and a Post Doctoral Research Worker.

Research Interests

Experience

Associate Dean International

2024-01-01 — Present

University of Southampton • Southampton, ENG

Overseeing international relations and accepting applications for PhD students.

Professor

2020-01-01 — Present

University of Southampton • Southampton, ENG

Leading research initiatives and teaching in Neurosciences.

Associate Professor

2014-01-01 — 2020-12-31

University of Southampton • Southampton, ENG

Contributed to research and education in Neurosciences.

Lecturer

2004-01-01 — 2014-12-31

University of Southampton • Southampton, ENG

Responsible for teaching and research in Neurosciences.

Research Fellow

2001-01-01 — 2004-12-31

Institute of Psychiatry, University of London • London, ENG

Conducted research on modeling tauopathies using Drosophila.

Post Doctoral Research Worker

1998-01-01 — 2001-12-31

Institute of Psychiatry, University of London • London, ENG

Investigated Wnt signaling in Alzheimer's Disease.