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Amy Lee is an Assistant Professor in the PhD Program in Biological Biomedical Sciences. Her research focuses on understanding gene regulation and the mechanisms through which cells sense and respond to environmental signals to modulate protein synthesis. The overarching goal of Lee's lab is to discover how gene-specific translation pathways influence cell fate decisions and how disruptions in these processes are linked to various human diseases, including developmental disorders and cancer. The lab employs an integrative approach that combines RNA-protein biochemistry, cell-based experiments, structural biology, and advanced sequencing technologies to obtain insights into the regulation of protein synthesis. By investigating the functions of RNA-binding proteins and translation factors in response to intrinsic and environmental cues, Lee aims to elucidate the molecular mechanisms underlying these processes and their implications for disease intervention.
Dana Farber Cancer Institute • Boston, MA
Researcher focusing on gene regulation and protein synthesis.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).