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Anastasia Nijnik is an Associate Professor in the Department of Physiology at McGill University. Her research focuses on the regulation of hematopoietic stem cell functions and lymphocyte differentiation, particularly in the context of immune response and the role of the histone deubiquitinase MYSM1. Her work investigates the processes involved in blood immune cell differentiation from hematopoietic stem cells in the bone marrow, with a specific focus on the molecular mechanisms regulating gene expression and DNA damage response signaling. The implications of her studies are significant for understanding human bone marrow failure syndromes and hematological malignancies. Nijnik's research program employs innovative transgenic mouse models to explore the immunomodulatory properties of natural and synthetic host-defense peptides and their potential activities in maintaining bone marrow health.
Department: Department of Medicine. Program: Experimental Medicine.