Dr. André Hoelz

Biography

André Hoelz is the Mary Charles Ferkel Professor of Chemistry at the California Institute of Technology since November 2010. His research focuses on structure-function studies of the nuclear pore complex and histone-modifying machinery, employing techniques such as X-ray crystallography and biochemical assays. Before joining Caltech, André was involved in pivotal studies at Günter Blobel's laboratory, where he initiated comprehensive structural-functional characterizations of the nuclear pore complex, a prominent feature in eukaryotic cells responsible for nucleocytoplasmic transport. His lab aims to elucidate the atomic structure of the nuclear pore complex, contributing novel insights into the underlying design principles of macromolecular assemblies. He earned his B.Sc. and M.Sc. from Albert-Ludwigs University of Freiburg, followed by a Ph.D. from Rockefeller University, where his academic prowess in biochemistry laid the foundation for his subsequent research achievements. Through his expert guidance, students at Caltech learn to express and purify recombinant proteins using modern biochemistry techniques, gaining hands-on experience and knowledge essential for their future careers in science.

Research Interests

Courses