Dr. André Hoelz

Professor

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Biography

André Hoelz is the Mary Charles Ferkel Professor of Chemistry at the California Institute of Technology. He specializes in structure-function studies of the nuclear pore complex and the histone-modifying machinery associated with it, utilizing techniques such as X-ray crystallography. With a comprehensive academic background, including a B.Sc. from Albert-Ludwigs University of Freiburg and a Ph.D. from Rockefeller University, Hoelz has been a faculty member at Caltech since November 2010. His research has contributed significantly to the understanding of macromolecular assemblies, particularly focusing on the atomic structure of the nuclear pore complex, one of the largest proteinaceous assemblies found in eukaryotic cells. Throughout his career, he has collaborated extensively, including work in Günter Blobel’s laboratory, where he developed interest in structural biology. In addition to his research, Hoelz teaches courses on biochemistry laboratory techniques, emphasizing the expression and purification of recombinant proteins in bacterial systems.

Research Interests

Courses

Biochemistry Laboratory

Requirements for California Institute of Technology

Doctorate Program
Requirements
TOEFL
Total
Required:100
IELTS
Overall
Required:7
Prerequisites
Bachelor's degree or equivalent Strong background in mathematics and physical sciences
Application Checklist
  • Online Application
  • Statement of Purpose
  • Three Letters of Recommendation
  • Transcripts
  • Resume/CV
Specialization Notes

Most Caltech graduate programs are PhD-only. GRE General and Subject tests vary by department; many have made them optional or no longer accept them.