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Andrea Amalfitano is the Osteopathic Heritage Foundation Endowed Chair in Osteopathic Medicine at Michigan State University. He completed his Ph.D. in 1989 and earned his D.O. in 1990, both from Michigan State University. His postdoctoral training includes Pediatrics at the Mayo Clinic (1991-93) and Pediatric Genetics at C.S. Mott Children's Hospital, University of Michigan (1993-96). Dr. Amalfitano's research focuses on the feasibility of gene transfer to treat both genetic and non-genetic diseases, with the aim of translating findings into clinical applications. He utilizes various methodologies to study diverse disease models, particularly in developing safe and effective gene transfer vectors, derived from a common cold virus (Adenovirus). His publications underscore the vector's ability to safely and efficiently deliver genetic information to various organs in living organisms. A significant challenge in gene transfer is the initiation of an innate immune response, and his recent work aims to identify the components of this response to allow safer gene transfer and improve vaccine applications, especially against HIV, malaria, and certain cancers. Additionally, he is exploring autoimmunity and how gene transfer techniques can enhance understanding and treatment of conditions like Ankylosing Spondylitis.
Department of Psychology