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Andrea Caporali is a Senior Lecturer at the University of Edinburgh, specializing in cardiovascular science. His research focuses on understanding the role of non-coding RNAs in the pathophysiology of vascular diseases and vascular regeneration. Non-coding RNAs have attracted significant attention in the field of vascular research, yet their critical regulatory elements and their targets among functionally related genes remain to be fully understood. To investigate these topics, Professor Caporali combines transcriptomic and functional genomic approaches with advanced imaging techniques. His laboratory aims to depict the role of newly identified non-coding RNAs in angiogenesis and vascular regeneration. By conducting loss-of-function studies and pre-clinical imaging, he characterizes the impact of selected non-coding RNA target genes on capillary growth and collateralization in both in vitro and in vivo models. Overall, his work aims to link the function of these newly identified non-coding RNAs with molecular signaling pathways and to describe their wider involvement in vascular regeneration.
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