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Andreas Schober is a principal investigator at IPEK University, specializing in experimental vascular medicine. His research focuses on the regulatory roles of microRNAs, particularly miR-21, in macrophage function and necrotic core formation in atherosclerotic plaques. He is particularly interested in the mechanisms through which microRNAs control energy metabolism and circadian apoptosis related to plaque progression. Furthermore, he is investigating the sex-specific role of autotaxin in the activity of endothelial cells and macrophages during atherogenesis. Schober's studies aim to explore how these cell types interact and contribute to the development of cardiovascular diseases. His team has published findings indicating that the size of the necrotic core in atherosclerotic plaques determines the risk of plaque rupture and cardiovascular events, such as myocardial infarctions, which tend to occur in the early morning. Through his innovative research, he seeks to identify promising therapeutic approaches to limit necrotic core expansion and prevent cardiovascular diseases.