Dr. Andres Jara Oseguera

Biography

Andres Jara-Oseguera is an Assistant Professor in the Department of Molecular Biosciences at the University of Texas at Austin. His research interests center on the function and regulation of ion channels, particularly their role in cellular electrical signaling. He focuses on understanding the complex three-dimensional structures of molecular machines and how their dynamic behaviors depend on amino acid sequences and biochemical environments. Jara-Oseguera studies the family of Transient Receptor Potential (TRP) channels, which are critical for a variety of biological processes. With 27 identified TRP channel genes in mammals, these transmembrane proteins play essential roles in systems throughout the human body, including immune function, bone formation, and sensory processes. His current projects include elucidating the mechanisms by which TRP channels detect multiple signals and serve as biological thermometers, contributing to understanding pain and inflammatory signaling. Through high-throughput mutagenesis and live-cell imaging, he aims to uncover how TRP channels respond to various stimuli and their regulatory mechanisms within sensory neurons. This innovative research is significant for elucidating the molecular basis of sensory detection and the implications of ion channel dysfunction in human diseases.

Research Interests

Experience