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Associate Professor Andrew Collins has over twenty years of research experience focused on antibody germline genes, antibody repertoire development, and antibody function. In 2015, his collaborators documented significant differences in germline heavy and light chain immunoglobulin genes among inbred mouse strains, suggesting that common laboratory mouse strains carry immunoglobulin gene loci that are mosaic fragments of subspecies of house mice with unusual breeding histories. His research indicates that the resulting 'mispairing' of heavy and light chain genes might explain certain autoimmune diseases in mouse models. Collins has highlighted that mouse and human antibody repertoires differ to meet their respective biological needs and proposed models that address the complex functionality of antibodies across different species. He remains active in various research groups and committees, including the Germline Gene Database Working Group and the Inferred Allele Review Committee for the Adaptive Immune Receptor Repertoire community. His professional experience includes key roles in institutions such as the Papua New Guinea Institute of Medical Research and Royal Children's Hospital in Melbourne, as well as lecture positions at UNSW since 1991.
University of New South Wales • Sydney, Australia
Teaching and conducting research in the field of immunology and antibody functions.
University of New South Wales • Sydney, Australia
Teaching and conducting research in the field of immunology.
Royal Children's Hospital • Melbourne, Australia
Research in pathology and immunology.
Collaborating Centre Epidemiology Diabetes Mellitus • Melbourne, Australia
Supporting research activities in epidemiology.
Papua New Guinea Institute of Medical Research • Goroka, Papua New Guinea
Overseeing research projects in medical research.
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