Dr. Andrew Doig

Biography

Andrew Doig is a Professor of Biochemistry at the University of Manchester, specializing in Alzheimer's Disease research and the mechanisms of toxic amyloid peptides. He holds a Doctor of Philosophy in Thermodynamics and Peptide Association Protein Folding from the University of Cambridge. His work delves into the aggregation of beta-amyloid peptides and their impact on neuronal cell death, driving his efforts in drug design to mitigate toxicity. He employs qualitative and quantitative proteomics and metabolomics to uncover protein responses to beta-amyloid exposure and aims to identify potential biomarkers and drug targets for Alzheimer's Disease. Additionally, he investigates the role of toxic amylin peptides in Type 2 diabetes, actively researching how these proteins affect pancreatic islet cells. Doig's contributions to the field include engineering de-immunised Green Fluorescent Protein for enhanced utility in gene expression studies, alongside advancing drug discovery through innovative methodologies in protein target identification.

Research Interests