Dr. Andrew Holland

Biography

Andrew Holland is a Professor in the Department of Molecular Biology & Genetics at Johns Hopkins University. His research focuses on cell division, a fundamental process forming the basis of life. His work investigates the molecular mechanisms that control accurate chromosome distribution and the role that mitotic errors play in human health and disease. The Holland lab employs a combination of chemical biology, biochemistry, and cell biology, utilizing genetically engineered mice to study pathways involved in mitosis and the effects on cellular and organism physiology. The major focus of the lab is to develop cell and animal-based models to study how defects in cell division contribute to genomic instability and tumorigenesis. The lab's research provides critical insights into how errors in chromosome distribution during mitosis can lead to abnormal chromosomal content in the resulting cells, potentially resulting in lethal growth defects and contributing to the development of cancer.

Research Interests