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The Pollack Lab focuses on translational genomics, particularly in the context of prostate diseases. The lab utilizes advanced methodologies such as next-generation sequencing, single-cell spatial genomics, and gene editing to model human cell and tissue responses, which aids in uncovering critical disease mechanisms and identifying biomarkers and therapeutic targets. Key areas of research include determining the disease mechanisms and identifying new therapeutic targets for benign prostatic hyperplasia (BPH), defining specific molecular features that distinguish between indolent and aggressive forms of prostate cancer, and investigating disease drivers in rare and neglected cancer types, including ameloblastoma and liposarcoma. The lab is involved in collaborations such as the Cancer Biology Program and the Bio-X Program, reflecting its commitment to pioneering research in cancer biology and genomics.
Focuses on Biomedical Data Science and informatics.