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Dr. Angus McQuibban is an Associate Professor in the Department of Biochemistry at the University of Toronto. His research is centered on mitochondrial quality control and the links between mitochondrial dysfunction and neurodegenerative diseases. Dr. McQuibban's work began with the identification of novel substrates for metalloproteinases, contributing significantly to our understanding of cancer metastasis. He later conducted research on mitochondrial proteolysis while at the MRC Laboratory of Molecular Biology in Cambridge, UK. He returned to Canada in 2005 to establish his own lab, focusing on the mechanisms of mitophagy—the process by which cells remove damaged mitochondria. This research is crucial for understanding how mitophagy impacts health outcomes, particularly in neurodegenerative diseases like Parkinson's disease (PD). His lab engages in both basic science research and translational studies aimed at developing novel therapeutics for these conditions.
Department of Sociology