Dr. Ann Haberman

Biography

Ann Haberman is an Associate Professor in the Department of Immunobiology at Yale School of Medicine. She earned her PhD in Immunology from the University of Pennsylvania in 1992. Her research focuses on the cellular and molecular interactions that regulate the formation and function of germinal centers, which are critical for antibody formation during the immune response. Germinal centers are large aggregates of B cells responding specifically to foreign substances, developing in the B cell follicles of the spleen and lymph nodes approximately one week after initial immunization or exposure to pathogens. These structures are sites of extreme metabolism and high proliferation and maturation rates, requiring intricate interactions between B cells and various cell types to achieve effective immune protection. Haberman's current research aims to elucidate the mechanism by which these interactions affect the expansion and effector output of B cells in germinal centers.

Research Interests

Experience