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Anna Marie Pyle is a Sterling Professor of Molecular, Cellular, and Developmental Biology at Yale University, where she also serves as an investigator for the Howard Hughes Medical Institute. Her research focuses on the structure and function of RNA, particularly large RNA molecules and their role in cellular processes. Pyle's lab employs a combination of experimental biochemistry, crystallography, and computational methods to study RNA structures and the enzymes that interact with them. Notably, her work has provided insights into the mechanisms of RNA splicing and the role of RNA in gene expression across various organisms. Pyle’s investigations into Group II introns have led to significant findings regarding RNA tertiary structures, contributing to the understanding of RNA's evolutionary significance. Furthermore, her studies on RNA-dependent ATPases have revealed their multifunctional roles in RNA metabolism and viral replication. Recognized for her contributions to the field, Pyle has received numerous accolades including the Blavatnik Fund Innovation Award and has been elected to prestigious associations such as the American Academy of Arts and Sciences.
Yale University • New Haven, CT
Member of Yale faculty, leading research in RNA structure and function.
Administered via the Graduate School of Arts and Sciences (GSAS). GRE General is optional for PhD.