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Anne Bassett is a Professor and Clinician Investigator at the University of Toronto, holding the Canada Research Chair in Schizophrenia Genetics. She is an internationally recognized leader in the study of genetics and schizophrenia, focusing on identifying and characterizing genetic subtypes of schizophrenia. A significant part of her research identifies a substantial proportion of patients with schizophrenia possessing inherited genetic changes, particularly involving major copy number variants. These structural genetic changes represent crucial mechanisms in schizophrenia and related congenital onset medical conditions. Her work on the 22q11.2 Deletion Syndrome (22q11.2DS), which serves as a prototype for multi-system disorders, has highlighted its identification as a powerful molecular risk factor for schizophrenia. Her research utilizes animal models, such as mice, to confirm and extend discoveries made in human studies, linking genetic findings to physical illnesses, cognitive function, brain imaging, neuropathology, and treatment response.
Department of Sociology