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Professor Annemiek van Spriel's research focuses on the role of tetraspanins in the immune system, their development, and their impact on cancer. Tetraspanins, located within the cell membrane, are crucial proteins that facilitate the formation of protein complexes, thereby ensuring proper cell function. There is a growing body of scientific evidence suggesting that tetraspanins play a significant role in cancer development; however, the precise mechanisms by which defects in these proteins lead to disease remain unclear. Van Spriel's group has made notable discoveries, such as the identification of the tetraspanin CD37, which protects against lymphoid malignancies. Her team is particularly interested in how tetraspanin networks affect the immune system in relation to cancer progression, with the overarching aim to uncover new insights regarding the cell membrane in both healthy individuals and cancer patients.
Radboud University • Nijmegen, Netherlands
Leading research in Experimental Immunology and directing a lab focused on the role of tetraspanins in immune system development and cancer.
Applies to Research Master's in Linguistics and Communication Sciences (Centre for Language Studies/Department of Language and Communication).