Dr. Arjen Jakobi

Biography

Arjen Jakobi is an associate professor in the Department of Bionanoscience at Delft University of Technology, part of the Kavli Institute of Nanoscience. He studied molecular sciences at Leiden University and the University of Erlangen, with a focus on applying computational quantum chemistry methods to structure-based drug design. His fascination with the complexity of protein structures led him to pursue experimental biophysics. During his doctoral studies at the Bijvoet Center for Biomolecular Research in Utrecht, he combined structural biology with single-molecule biophysics to understand the regulatory mechanisms of nanoscale mechanosensory proteins involved in bleeding arrest. He joined the European Molecular Biology Laboratory (EMBL) where he utilized electron cryo-microscopy (cryo-EM) to study large molecular assemblies that play roles in selective autophagy. His research goal is to unveil how cells build autonomous immunity using membrane remodeling machinery. Since starting his own group in 2018, he focuses on understanding highly dynamic processes within cells using advanced imaging techniques. His lab aims to develop new strategies for fighting pathogens that are otherwise challenging to target.

Research Interests

Courses