Dr. Arlene Chapman

Biography

Arlene Beth Chapman, MD, is a distinguished nephrologist at the University of Chicago and serves as the Chief of the Section of Nephrology. Her clinical and research interests focus on hereditary kidney diseases, particularly autosomal dominant polycystic kidney disease (ADPKD), essential hypertension, and the intersection of kidney function and pregnancy. Over the past decades, Dr. Chapman has been a leading figure in ADPKD research, notably contributing to the development of magnetic resonance imaging techniques for assessing total kidney volume (TKV), a key biomarker of disease progression. Her work has been instrumental in advancing clinical trials for novel therapies, including vasopressin V2 receptor antagonists and strategies for rigorous blood pressure control. In recognition of her significant contributions, Dr. Chapman received the 2020 Lillian Jean Kaplan International Prize from the International Society of Nephrology, honoring her pioneering efforts in ADPKD research and her leadership in interventional clinical trials that led to FDA-approved treatments. She is also the Associate Director of the Institute for Translational Medicine and the Director of the Clinical Research Center at the University of Chicago, where she established a whole room calorimetry core for energy expenditure and metabolism studies. Dr. Chapman is a dedicated educator and mentor, actively involved in training medical students, residents, and fellows, and has published over 200 peer-reviewed articles and 20 book chapters.

Research Interests

Experience

Awards