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Aron B. Fisher, M.D. is an Emeritus Professor in the Department of Physiology at the University of Pennsylvania's Perelman School of Medicine. He has a distinguished academic career and extensive research expertise in the field of physiological processes related to oxidative stress and reactive oxygen species. Dr. Fisher's research focuses on understanding the pathways involved in the generation of reactive oxygen species, particularly in response to altered blood flow conditions such as lung ischemia and reperfusion. His laboratory utilizes a variety of models, including isolated perfused lung models in rats and mice, to study the effects of pulmonary embolism and associated lung transplantation. His investigations cover the implications of cell signaling pathways activated by shear stress, the role of peroxiredoxin 6 as an antioxidant and its bifunctional properties as a glutathione peroxidase and phospholipase A2. Dr. Fisher's work has significant implications for elucidating oxidative stress's impact on lung tissue and developing therapeutic strategies for related conditions.
University of Pennsylvania • Philadelphia, PA
Professor in the Department of Physiology specializing in oxidative stress and cellular signaling.
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