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Arvin Dar, PhD, is the Benno C. Schmidt Chair of Cancer Research at the Sloan Kettering Institute. His lab's research focuses on exploring cancer mechanisms and developing novel approaches in chemical biology. Dr. Dar's work integrates various disciplines including genetics, biochemistry, and structural biology to discover small molecules that modulate cell signaling networks, which are instrumental in understanding disease mechanisms and therapeutic applications. He has developed chemical switches and conformational modulators that can selectively bind to specific targets of interest, influencing the formation of particular states in complexes. A significant aspect of his research includes the use of molecular glues that operate at the interface of biomolecular complexes to regulate their assembly and function in signal transduction. Overall, his laboratory is dedicated to creating chemical tools and probes that specifically target cancers driven by dysregulated enzymes, receptors, and other key pathways that contribute to cancer development and progression.
The program is hosted by the Weill Cornell Graduate School of Medical Sciences in partnership with the Sloan Kettering Institute. GRE scores are optional.