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Originally a biochemist, Professor Al-Shamkhani became interested in immunology during his postdoctoral training at the University of Oxford. He joined the University of Southampton in 1998 as a Lecturer and has progressed to become a Professor of Immunology in the School of Cancer Sciences, currently based at the Centre for Cancer Immunology. His research focuses on understanding the receptors and signalling pathways that regulate T cell responses, with the aim of developing innovative strategies to enhance anti-tumour immunity. His work encompasses key areas such as immunobiology, costimulatory receptors, and the development of antibody therapies targeting these receptors. Ongoing studies include the characterization of immune responses in human solid cancers and defining the factors that drive immune evasion and resistance to immunotherapy. Professor Al-Shamkhani actively supervises PhD students and collaborates with various researchers on projects focused on developing immunostimulatory antibodies and advancing cancer treatments.
University of Southampton • Southampton, England
Leading research in the field of immunology focusing on cancer and T cell responses.