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Professor Moffatt started her research career as a postdoctoral fellow investigating adenine phosphoribosyltransferase (APT) and its predominant isoform, APT1, which causes male sterility in plants. Upon returning to her work on enzyme activity, she identified a fertile APT1-deficient mutant, leading to current studies on dual transcripts arising from the APT1 locus. Her research focuses on the functional significance of APT products in plant physiology, particularly regarding the role of APT1 in stress tolerance compared to wild-type plants. Professor Moffatt's group investigates the roles of adenosine kinase (ADK) in plants, demonstrating that deficiency in ADK critically impacts methylation activities and cytokinin metabolism. Recent projects have also examined mutants deficient in methylthioadenosine (MTA) nucleosidase activity, revealing their association with male and female sterility, abnormal vascular development, and reduced auxin transport. She collaborates with other researchers on transcriptomic and metabolomic analyses of the naturally stress-tolerant plant, Eutrema salsuginea. Professor Moffatt welcomes motivated graduate students to inquire about research participation.
University of Waterloo • Waterloo, ON, Canada
Teaching and research in the Department of Biology.
Includes fields like Clinical, Cognitive, Developmental, and Industrial/Organizational Psychology.