Dr. Bass Hassan

Biography

Bass Hassan is a researcher in the Medical Sciences Division at the University of Oxford, focusing on the structure and function of genes regulating tumor phenotypes. His work emphasizes the importance of understanding cellular pathways that are deregulated in tumors due to gene disruptions, which alter the growth propensity of tumor cells and facilitate their invasion and spread in the body. His research on reciprocally imprinted genes, particularly IGF2 and IGF2R, reveals significant insights into mammalian development and cancer progression, where his studies indicate that alterations in these genes can act as progression factors in early tumor formation. He has also explored the roles of E-cadherin and other genes in the epithelial-mesenchymal transition (EMT), a critical process in later-stage cancers. Targeting the pathways involved in EMT presents new opportunities for cancer prevention and treatment. His involvement with the EuroSarc consortium underlines his commitment to advancing understanding and treatment of rare tumors like Ewing sarcoma through innovative genomic techniques. His team's research spans both basic and translational studies, indicating a strong commitment to bridging the gap between laboratory findings and clinical applications.

Research Interests