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Ben Berks is a prominent researcher in the field of Biochemistry, specializing in the study of bacterial cell envelope processes. His work employs a multi-disciplinary approach to understand the molecular machines involved in the formation of cell envelopes in Gram-negative bacteria, emphasizing the systems that move proteins across the cell envelope. Berks’ group focuses on critical areas including the Type IX secretion system (T9SS), which plays a significant role in severe dental disease and the maintenance of a healthy gut microbiota, and the Tat (twin-arginine translocation) protein transport system, which is essential for various cellular processes in bacteria and is linked to pathogen virulence. He is also interested in the physical properties of the periplasm and how the composition and function of the outer membrane vary across bacterial kingdoms. His research incorporates advanced techniques such as single molecule fluorescence imaging, alongside collaborative structural analysis of nanomachines using cryo-electron microscopy. Berks aims to elucidate the mechanistic workings of these systems, contributing to a deeper understanding of bacterial pathogenesis and antibiotic resistance.
Department of Politics and International Relations - Higher Level English requirement.